Interferon action and apoptosis are defective in mice devoid of 2',5'-oligoadenylate-dependent RNase L.

2',5'-Oligoadenylate-dependent RNase L functions in the interferon-inducible, RNA decay pathway known as the 2-5A system. To determine the physiological roles of the 2-5A system, mice were generated with a targeted disruption of the RNase L gene. The antiviral effect of interferon alpha wa...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Zhou, A, Paranjape, J, Brown, T L, Nie, H, Naik, S, Dong, B, Chang, A, Trapp, B, Fairchild, R, Colmenares, C, Silverman, R H
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 1997
Aiheet:
Research Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC1170242/
https://ncbi.nlm.nih.gov/pubmed/9351818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/16.21.6355
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