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Conserved Nucleotides within the J Domain of the Encephalomyocarditis Virus Internal Ribosome Entry Site Are Required for Activity and for Interaction with eIF4G

The internal ribosome entry site (IRES) elements of cardioviruses (e.g., encephalomyocarditis virus [EMCV] and foot-and-mouth disease virus) are predicted to have very similar secondary structures. Among these complex RNA structures there is only rather limited complete sequence conservation. Within...

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Detalles Bibliográficos
Main Authors: Clark, Angela T., Robertson, Morwenna E. M., Conn, Graeme L., Belsham, Graham J.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2003
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC262551/
https://ncbi.nlm.nih.gov/pubmed/14610168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.77.23.12441-12449.2003
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