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Foot-and-Mouth Disease Virus 3C Protease Induces Cleavage of Translation Initiation Factors eIF4A and eIF4G within Infected Cells

Infection of cells by foot-and-mouth disease virus (FMDV) results in the rapid inhibition of host cell protein synthesis. This process is accompanied by the early cleavage of the translation initiation factor eIF4G, a component of the cap-binding complex eIF4F. This cleavage is mediated by the leade...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Belsham, Graham J., McInerney, Gerald M., Ross-Smith, Natalie
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2000
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC111537/
https://ncbi.nlm.nih.gov/pubmed/10590115
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