Cleavage of Eukaryotic Translation Initiation Factor 4GII within Foot-and-Mouth Disease Virus-Infected Cells: Identification of the L-Protease Cleavage Site In Vitro

Foot-and-mouth disease virus (FMDV) induces a very rapid inhibition of host cell protein synthesis within infected cells. This is accompanied by the cleavage of the eukaryotic translation initiation factor 4GI (eIF4GI). The cleavage of the related protein eIF4GII has now been analyzed. Within FMDV-i...

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Detalhes bibliográficos
Main Authors: Gradi, Alessandra, Foeger, Nicole, Strong, Rebecca, Svitkin, Yuri V., Sonenberg, Nahum, Skern, Tim, Belsham, Graham J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2004
Assuntos:
Virus-Cell Interactions
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC371048/
https://ncbi.nlm.nih.gov/pubmed/15016848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.78.7.3271-3278.2004
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