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Functional dichotomy in the 16S rRNA (m(1)A1408) methyltransferase family and control of catalytic activity via a novel tryptophan mediated loop reorganization
Methylation of the bacterial small ribosomal subunit (16S) rRNA on the N1 position of A1408 confers exceptionally high-level resistance to a broad spectrum of aminoglycoside antibiotics. Here, we present a detailed structural and functional analysis of the Catenulisporales acidiphilia 16S rRNA (m(1)...
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| Publicado no: | Nucleic Acids Res |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4705659/ https://ncbi.nlm.nih.gov/pubmed/26609134 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkv1306 |
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