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Critical Residues for Cofactor Binding and Catalytic Activity in the Aminoglycoside Resistance Methyltransferase Sgm
The 16S rRNA methyltransferase Sgm from “Micromonospora zionensis” confers resistance to aminoglycoside antibiotics by specific modification of the 30S ribosomal A site. Sgm is a member of the FmrO family, distant relatives of the S-adenosyl-l-methionine (SAM)-dependent RNA subfamily of methyltransf...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology (ASM)
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2519519/ https://ncbi.nlm.nih.gov/pubmed/18586937 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00076-08 |
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