Brk/Protein Tyrosine Kinase 6 Phosphorylates p27(KIP1), Regulating the Activity of Cyclin D–Cyclin-Dependent Kinase 4

Cyclin D and cyclin-dependent kinase 4 (cdk4) are overexpressed in a variety of tumors, but their levels are not accurate indicators of oncogenic activity because an accessory factor such as p27(Kip1) is required to assemble this unstable dimer. Additionally, tyrosine (Y) phosphorylation of p27 (pY8...

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Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Biol
Egile Nagusiak: Patel, Priyank, Asbach, Benedikt, Shteyn, Elina, Gomez, Cindy, Coltoff, Alexander, Bhuyan, Sadia, Tyner, Angela L., Wagner, Ralf, Blain, Stacy W.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Microbiology 2015
Gaiak:
Articles
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4387217/
https://ncbi.nlm.nih.gov/pubmed/25733683
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01206-14
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