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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)

Proliferation and apoptosis are increased in many types of inflammatory diseases. A role for the cyclin kinase inhibitor p27(Kip1) (p27) in limiting proliferation has been shown. In this study, we show that p27(–/–) mesangial cells and fibroblasts have strikingly elevated rates of apoptosis, not pro...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hiromura, Keiju, Pippin, Jeffrey W., Fero, Matthew L., Roberts, James M., Shankland, Stuart J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1999
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC408127/
https://ncbi.nlm.nih.gov/pubmed/10074476
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