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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)
Proliferation and apoptosis are increased in many types of inflammatory diseases. A role for the cyclin kinase inhibitor p27(Kip1) (p27) in limiting proliferation has been shown. In this study, we show that p27(–/–) mesangial cells and fibroblasts have strikingly elevated rates of apoptosis, not pro...
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| Главные авторы: | , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
American Society for Clinical Investigation
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC408127/ https://ncbi.nlm.nih.gov/pubmed/10074476 |
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