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Modulation of apoptosis by the cyclin-dependent kinase inhibitor p27(Kip1)
Proliferation and apoptosis are increased in many types of inflammatory diseases. A role for the cyclin kinase inhibitor p27(Kip1) (p27) in limiting proliferation has been shown. In this study, we show that p27(–/–) mesangial cells and fibroblasts have strikingly elevated rates of apoptosis, not pro...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Clinical Investigation
1999
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC408127/ https://ncbi.nlm.nih.gov/pubmed/10074476 |
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