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p27(Kip1) Inhibits Cyclin D-Cyclin-Dependent Kinase 4 by Two Independent Modes

Cell cycle progression is regulated by cyclin-dependent kinases (cdk's), which in turn are regulated by their interactions with stoichiometric inhibitors, such as p27(Kip1). Although p27 associates with cyclin D-cyclin-dependent kinase 4 (cdk4) constitutively, whether or not it inhibits this co...

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Detalhes bibliográficos
Main Authors: Ray, Arpita, James, Melissa K., Larochelle, Stéphane, Fisher, Robert P., Blain, Stacy W.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2643810/
https://ncbi.nlm.nih.gov/pubmed/19075005
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.00898-08
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