Rise and fall of subclones from diagnosis to relapse in pediatric B-acute lymphoblastic leukaemia

There is incomplete understanding of genetic heterogeneity and clonal evolution during cancer progression. Here we use deep whole-exome sequencing to describe the clonal architecture and evolution of 20 pediatric B-acute lymphoblastic leukaemias from diagnosis to relapse. We show that clonal diversi...

全面介紹

Na minha lista:
書目詳細資料
發表在:Nat Commun
Main Authors: Ma, Xiaotu, Edmonson, Michael, Yergeau, Donald, Muzny, Donna M., Hampton, Oliver A., Rusch, Michael, Song, Guangchun, Easton, John, Harvey, Richard C., Wheeler, David A., Ma, Jing, Doddapaneni, HarshaVardhan, Vadodaria, Bhavin, Wu, Gang, Nagahawatte, Panduka, Carroll, William L., Chen, I-Ming, Gastier-Foster, Julie M., Relling, Mary V., Smith, Malcolm A., Devidas, Meenakshi, Auvil, Jaime M. Guidry, Downing, James R., Loh, Mignon L., Willman, Cheryl L., Gerhard, Daniela S., Mullighan, Charles G., Hunger, Stephen P., Zhang, Jinghui
格式: Artigo
語言:Inglês
出版: Nature Pub. Group 2015
主題:
Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4377644/
https://ncbi.nlm.nih.gov/pubmed/25790293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7604
標簽: 添加標簽
沒有標簽, 成為第一個標記此記錄!

相似書籍