Kinetic Mechanism and the Rate-limiting Step of Plasmodium vivax Serine Hydroxymethyltransferase

Serine hydroxymethyltransferase (SHMT) is a pyridoxal 5′-phosphate (PLP)-dependent enzyme that catalyzes a hydroxymethyl group transfer from l-serine to tetrahydrofolate (H(4)folate) to yield glycine and 5,10-methylenetetrahydrofolate (CH(2)-H(4)folate). SHMT is crucial for deoxythymidylate biosynth...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Biol Chem
Main Authors: Maenpuen, Somchart, Amornwatcharapong, Watcharee, Krasatong, Pasupat, Sucharitakul, Jeerus, Palfey, Bruce A., Yuthavong, Yongyuth, Chitnumsub, Penchit, Leartsakulpanich, Ubolsree, Chaiyen, Pimchai
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2015
Teme:
Enzymology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375514/
https://ncbi.nlm.nih.gov/pubmed/25678710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M114.612275
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki