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Notch Regulates Cytolytic Effector Function in CD8(+) T Cells
The maturation of naive CD8(+) T cells into effector CTLs is a critical feature of a functional adaptive immune system. Development of CTLs depends, in part, upon the expression of the transcriptional regulator eomesodermin (EOMES), which is thought to regulate expression of two key effector molecul...
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| Veröffentlicht in: | J Immunol |
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| Hauptverfasser: | , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2009
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374745/ https://ncbi.nlm.nih.gov/pubmed/19265115 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802598 |
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