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Notch Regulates Cytolytic Effector Function in CD8(+) T Cells

The maturation of naive CD8(+) T cells into effector CTLs is a critical feature of a functional adaptive immune system. Development of CTLs depends, in part, upon the expression of the transcriptional regulator eomesodermin (EOMES), which is thought to regulate expression of two key effector molecul...

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Dades bibliogràfiques
Publicat a:J Immunol
Autors principals: Cho, Ok Hyun, Shin, Hyun Mu, Miele, Lucio, Golde, Todd E., Fauq, Abdul, Minter, Lisa M., Osborne, Barbara A.
Format: Artigo
Idioma:Inglês
Publicat: 2009
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374745/
https://ncbi.nlm.nih.gov/pubmed/19265115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.0802598
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