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Notch1 augments NF-κB activity by facilitating its nuclear retention

Notch1 specifically upregulates expression of the cytokine interferon-γ in peripheral T cells through activation of NF-κB. However, how Notch mediates NF-κB activation remains unclear. Here, we examined the temporal relationship between Notch signaling and NF-κB induction during T-cell activation. N...

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Sonraí Bibleagrafaíochta
Main Authors: Shin, Hyun Mu, Minter, Lisa M, Cho, Ok Hyun, Gottipati, Sridevi, Fauq, Abdul H, Golde, Todd E, Sonenshein, Gail E, Osborne, Barbara A
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2006
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1356346/
https://ncbi.nlm.nih.gov/pubmed/16319921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600902
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