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Notch1 augments NF-κB activity by facilitating its nuclear retention
Notch1 specifically upregulates expression of the cytokine interferon-γ in peripheral T cells through activation of NF-κB. However, how Notch mediates NF-κB activation remains unclear. Here, we examined the temporal relationship between Notch signaling and NF-κB induction during T-cell activation. N...
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| Autors principals: | , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2006
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1356346/ https://ncbi.nlm.nih.gov/pubmed/16319921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7600902 |
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