CD28 Signaling Drives Notch Ligand Expression on CD4 T Cells

Notch signaling provides an important cue in the mammalian developmental process. It is a key player in T cell development and function. Notch ligands such as Delta-like ligands (DLL) 1, 3, 4, and JAG1, 2 can impact Notch signaling positively or negatively, by trans-activation or cis-inhibition. Tra...

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Udgivet i:Front Immunol
Main Authors: Mitra, Ankita, Shanthalingam, Sudarvili, Sherman, Heather L., Singh, Khushboo, Canakci, Mine, Torres, Joe A., Lawlor, Rebecca, Ran, Yong, Golde, Todd E., Miele, Lucio, Thayumanavan, Sankaran, Minter, Lisa M., Osborne, Barbara A.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7221189/
https://ncbi.nlm.nih.gov/pubmed/32457739
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2020.00735
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