Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides

α-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the activation and expansion of human iNKT cells. The key challenge in the synthesis of both target molecules was the stereoselective synthesis of the α-glycosidic linkage. Of the methods examined, glycos...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Bioorg Med Chem Lett
Autores principales: Jervis, Peter J., Veerapen, Natacha, Bricard, Gabriel, Cox, Liam R., Porcelli, Steven A., Besra, Gurdyal S.
Formato: Artigo
Lenguaje:Inglês
Publicado: Elsevier Science Ltd 2010
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374101/
https://ncbi.nlm.nih.gov/pubmed/20529677
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.05.010
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares