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Synthesis and biological activity of α-glucosyl C24:0 and C20:2 ceramides
α-Glucosyl ceramides 4 and 5 have been synthesised and evaluated for their ability to stimulate the activation and expansion of human iNKT cells. The key challenge in the synthesis of both target molecules was the stereoselective synthesis of the α-glycosidic linkage. Of the methods examined, glycos...
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| Publicado no: | Bioorg Med Chem Lett |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier Science Ltd
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4374101/ https://ncbi.nlm.nih.gov/pubmed/20529677 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.05.010 |
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