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Kinetic characterization of human butyrylcholinesterase mutants for hydrolysis of cocaethylene
It is known that majority of cocaine users also consume alcohol. Alcohol can react with cocaine to produce a significantly more cytotoxic compound, cocaethylene. Hence, a truly valuable cocaine-metabolizing enzyme for cocaine abuse/overdose treatment should be efficient for not only cocaine itself,...
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| Veröffentlicht in: | Biochem J |
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| Hauptverfasser: | , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4371731/ https://ncbi.nlm.nih.gov/pubmed/24870023 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20140360 |
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