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Kinetic Characterization of a Cocaine Hydrolase Engineered from Mouse Butyrylcholinesterase
Mouse butyrylcholinesterase (mBChE) and an mBChE-based cocaine hydrolase (mCocH, i.e. the A199S/S227A/S287G/A328W/Y332G mutant) have been characterized for their catalytic activities against cocaine, i.e. naturally occurring (−)-cocaine, in comparison with the corresponding human BChE (hBChE) and an...
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| Publicado no: | Biochem J |
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| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4367957/ https://ncbi.nlm.nih.gov/pubmed/25486543 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20141266 |
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