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Substrate Selectivity of High-Activity Mutants of Human Butyrylcholinesterase

Cocaine is one of the most addictive drugs, and there is still no FDA (Food and Drug Administration)-approved medication specific for cocaine. A promising therapeutic strategy is to accelerate cocaine metabolism producing biologically inactive metabolites via a route similar to the primary cocaine-m...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Hou, Shurong, Xue, Liu, Yang, Wenchao, Fang, Lei, Zheng, Fang, Zhan, Chang-Guo
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3836059/
https://ncbi.nlm.nih.gov/pubmed/24077614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c3ob41713a
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