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Characterization of a high-activity mutant of human butyrylcholinesterase against (-)-cocaine

Cocaine addiction and overdose are a well-known public health problem. There is no approved medication available for cocaine abuse treatment. Our recently designed and discovered high-activity mutant (A199S/S287G/A328W/Y332G) of human butyrylcholinesterase (BChE) has been recognized to be worth expl...

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Detalhes bibliográficos
Main Authors: Yang, Wenchao, Xue, Liu, Fang, Lei, Chen, Xi, Zhan, Chang-Guo
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2891156/
https://ncbi.nlm.nih.gov/pubmed/20060817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2010.01.004
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