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Amino-Acid Mutations to Extend the Biological Half-life of a Therapeutically Valuable Mutant of Human Butyrylcholinesterase
Cocaine is a widely abused and addictive drug without an FDA-approved medication. Our recently designed and discovered cocaine hydrolase, particularly E12-7 engineered from human butyrylcholinesterase (BChE), has the promise of becoming a valuable cocaine abuse treatment. An ideal anti-cocaine thera...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3996703/ https://ncbi.nlm.nih.gov/pubmed/24582612 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cbi.2014.02.007 |
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