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Codon optimality is a major determinant of mRNA stability
Messenger RNA degradation represents a critical regulated step in gene expression. While the major pathways in turnover have been identified, accounting for disparate half-lives has been elusive. We show that codon optimality is one feature that contributes greatly to mRNA stability. Genome-wide RNA...
में बचाया:
| में प्रकाशित: | Cell |
|---|---|
| मुख्य लेखकों: | , , , , , , , , , , |
| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
2015
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359748/ https://ncbi.nlm.nih.gov/pubmed/25768907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.029 |
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