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Codon and amino acid content are associated with mRNA stability in mammalian cells
Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in the cell and is a major control point for modulating gene expression. In yeast and other model organisms, codon identity is a powerful determinant of transcript stability, contributing broadly to impact half-li...
Enregistré dans:
| Publié dans: | PLoS One |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2020
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7018022/ https://ncbi.nlm.nih.gov/pubmed/32053646 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228730 |
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