Codon and amino acid content are associated with mRNA stability in mammalian cells

Messenger RNA (mRNA) degradation plays a critical role in regulating transcript levels in the cell and is a major control point for modulating gene expression. In yeast and other model organisms, codon identity is a powerful determinant of transcript stability, contributing broadly to impact half-li...

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Detaylı Bibliyografya
Yayımlandı:PLoS One
Asıl Yazarlar: Forrest, Megan E., Pinkard, Otis, Martin, Sophie, Sweet, Thomas J., Hanson, Gavin, Coller, Jeff
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2020
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7018022/
https://ncbi.nlm.nih.gov/pubmed/32053646
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0228730
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