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Codon optimality is a major determinant of mRNA stability
Messenger RNA degradation represents a critical regulated step in gene expression. While the major pathways in turnover have been identified, accounting for disparate half-lives has been elusive. We show that codon optimality is one feature that contributes greatly to mRNA stability. Genome-wide RNA...
שמור ב:
| הוצא לאור ב: | Cell |
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| Main Authors: | , , , , , , , , , , |
| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2015
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4359748/ https://ncbi.nlm.nih.gov/pubmed/25768907 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2015.02.029 |
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