Apoptosis suppressor ARC modulates SMAC mimetic-induced cell death through BIRC2/MAP3K14 signalling in acute myeloid leukaemia

Overexpression of the apoptosis repressor with caspase recruitment domain (ARC, also termed NOL3) protein predicts adverse outcome in patients with acute myeloid leukaemia (AML) and confers drug resistance to AML cells. The second mitochondrial-derived activator of caspases (SMAC, also termed DIABLO...

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Pubblicato in:Br J Haematol
Autori principali: Mak, Po Yee, Mak, Duncan H., Ruvolo, Vivian, Jacamo, Rodrigo, Kornblau, Steven M., Andreeff, Michael, Carter, Bing Z.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2014
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4357400/
https://ncbi.nlm.nih.gov/pubmed/25079338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bjh.13054
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