Anti-apoptotic ARC protein confers chemoresistance by controlling leukemia-microenvironment interactions through a NFκB/IL1β signaling network

To better understand how the apoptosis repressor with caspase recruitment domain (ARC) protein confers drug resistance in acute myeloid leukemia (AML), we investigated the role of ARC in regulating leukemia-mesenchymal stromal cell (MSC) interactions. In addition to the previously reported effect on...

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Bibliographic Details
Published in:Oncotarget
Main Authors: Carter, Bing Z., Mak, Po Yee, Chen, Ye, Mak, Duncan H., Mu, Hong, Jacamo, Rodrigo, Ruvolo, Vivian, Arold, Stefan T., Ladbury, John E., Burks, Jared K., Kornblau, Steven, Andreeff, Michael
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2016
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4991438/
https://ncbi.nlm.nih.gov/pubmed/26956049
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7911
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