Rapid Drug Tolerance and Dramatic Sterilizing Effect of Moxifloxacin Monotherapy in a Novel Hollow-Fiber Model of Intracellular Mycobacterium kansasii Disease

Mycobacterium kansasii is the second most common mycobacterial cause of lung disease. Standard treatment consists of rifampin, isoniazid, and ethambutol for at least 12 months after negative sputum. Thus, shorter-duration therapies are needed. Moxifloxacin has good MICs for M. kansasii. However, goo...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Antimicrob Agents Chemother
Main Authors: Srivastava, Shashikant, Pasipanodya, Jotam, Sherman, Carleton M., Meek, Claudia, Leff, Richard, Gumbo, Tawanda
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Experimental Therapeutics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356829/
https://ncbi.nlm.nih.gov/pubmed/25645830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04441-14
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