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Rapid Drug Tolerance and Dramatic Sterilizing Effect of Moxifloxacin Monotherapy in a Novel Hollow-Fiber Model of Intracellular Mycobacterium kansasii Disease

Mycobacterium kansasii is the second most common mycobacterial cause of lung disease. Standard treatment consists of rifampin, isoniazid, and ethambutol for at least 12 months after negative sputum. Thus, shorter-duration therapies are needed. Moxifloxacin has good MICs for M. kansasii. However, goo...

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書誌詳細
出版年:Antimicrob Agents Chemother
主要な著者: Srivastava, Shashikant, Pasipanodya, Jotam, Sherman, Carleton M., Meek, Claudia, Leff, Richard, Gumbo, Tawanda
フォーマット: Artigo
言語:Inglês
出版事項: American Society for Microbiology 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356829/
https://ncbi.nlm.nih.gov/pubmed/25645830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04441-14
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