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Rapid Drug Tolerance and Dramatic Sterilizing Effect of Moxifloxacin Monotherapy in a Novel Hollow-Fiber Model of Intracellular Mycobacterium kansasii Disease

Mycobacterium kansasii is the second most common mycobacterial cause of lung disease. Standard treatment consists of rifampin, isoniazid, and ethambutol for at least 12 months after negative sputum. Thus, shorter-duration therapies are needed. Moxifloxacin has good MICs for M. kansasii. However, goo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Srivastava, Shashikant, Pasipanodya, Jotam, Sherman, Carleton M., Meek, Claudia, Leff, Richard, Gumbo, Tawanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356829/
https://ncbi.nlm.nih.gov/pubmed/25645830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.04441-14
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