Amikacin Optimal Exposure Targets in the Hollow-Fiber System Model of Tuberculosis

Aminoglycosides such as amikacin are currently used for the treatment of multidrug-resistant tuberculosis (MDR-TB). However, formal pharmacokinetic/pharmacodynamic (PK/PD) studies to identify amikacin exposures and dosing schedules that optimize Mycobacterium tuberculosis killing have not been perfo...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Srivastava, Shashikant, Modongo, Chawanga, Siyambalapitiyage Dona, Chandima W., Pasipanodya, Jotam G., Deshpande, Devyani, Gumbo, Tawanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5038304/
https://ncbi.nlm.nih.gov/pubmed/27458215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00961-16
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