Moxifloxacin's Limited Efficacy in the Hollow-Fiber Model of Mycobacterium abscessus Disease

Current regimens used to treat pulmonary Mycobacterium abscessus disease have limited efficacy. There is an urgent need for new drugs and optimized combinations and doses. We performed hollow-fiber-system studies in which M. abscessus was exposed to moxifloxacin lung concentration-time profiles simi...

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Detalles Bibliográficos
Publicado en:Antimicrob Agents Chemother
Autores principales: Ferro, Beatriz E., Srivastava, Shashikant, Deshpande, Devyani, Pasipanodya, Jotam G., van Soolingen, Dick, Mouton, Johan W., van Ingen, Jakko, Gumbo, Tawanda
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2016
Materias:
Experimental Therapeutics
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879399/
https://ncbi.nlm.nih.gov/pubmed/27067317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02821-15
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