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Moxifloxacin's Limited Efficacy in the Hollow-Fiber Model of Mycobacterium abscessus Disease

Current regimens used to treat pulmonary Mycobacterium abscessus disease have limited efficacy. There is an urgent need for new drugs and optimized combinations and doses. We performed hollow-fiber-system studies in which M. abscessus was exposed to moxifloxacin lung concentration-time profiles simi...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Ferro, Beatriz E., Srivastava, Shashikant, Deshpande, Devyani, Pasipanodya, Jotam G., van Soolingen, Dick, Mouton, Johan W., van Ingen, Jakko, Gumbo, Tawanda
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2016
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879399/
https://ncbi.nlm.nih.gov/pubmed/27067317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02821-15
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