Moxifloxacin's Limited Efficacy in the Hollow-Fiber Model of Mycobacterium abscessus Disease

Current regimens used to treat pulmonary Mycobacterium abscessus disease have limited efficacy. There is an urgent need for new drugs and optimized combinations and doses. We performed hollow-fiber-system studies in which M. abscessus was exposed to moxifloxacin lung concentration-time profiles simi...

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Sparad:
Bibliografiska uppgifter
I publikationen:Antimicrob Agents Chemother
Huvudupphovsmän: Ferro, Beatriz E., Srivastava, Shashikant, Deshpande, Devyani, Pasipanodya, Jotam G., van Soolingen, Dick, Mouton, Johan W., van Ingen, Jakko, Gumbo, Tawanda
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology 2016
Ämnen:
Experimental Therapeutics
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4879399/
https://ncbi.nlm.nih.gov/pubmed/27067317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.02821-15
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