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High-throughput screening to identify inhibitors of lysine demethylases

Lysine demethylases (KDMs) are epigenetic regulators whose dysfunction is implicated in the pathology of many human diseases including various types of cancer, inflammation and X-linked intellectual disability. Particular demethylases have been identified as promising therapeutic targets, and tremen...

詳細記述

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書誌詳細
出版年:Epigenomics
主要な著者: Gale, Molly, Yan, Qin
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356004/
https://ncbi.nlm.nih.gov/pubmed/25687466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.14.63
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