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High-throughput screening to identify inhibitors of lysine demethylases

Lysine demethylases (KDMs) are epigenetic regulators whose dysfunction is implicated in the pathology of many human diseases including various types of cancer, inflammation and X-linked intellectual disability. Particular demethylases have been identified as promising therapeutic targets, and tremen...

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Detalhes bibliográficos
Publicado no:Epigenomics
Main Authors: Gale, Molly, Yan, Qin
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356004/
https://ncbi.nlm.nih.gov/pubmed/25687466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.14.63
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