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High-throughput screening to identify inhibitors of lysine demethylases

Lysine demethylases (KDMs) are epigenetic regulators whose dysfunction is implicated in the pathology of many human diseases including various types of cancer, inflammation and X-linked intellectual disability. Particular demethylases have been identified as promising therapeutic targets, and tremen...

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Detalles Bibliográficos
Publicado en:Epigenomics
Main Authors: Gale, Molly, Yan, Qin
Formato: Artigo
Idioma:Inglês
Publicado: 2015
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4356004/
https://ncbi.nlm.nih.gov/pubmed/25687466
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/epi.14.63
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