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New Inhibitors of ABCG2 Identified by High-throughput Screening
In order to identify novel inhibitors of the ATP-binding cassette transporter ABCG2, a high throughput assay measuring accumulation of the ABCG2 substrate pheophorbide a in ABCG2 overexpressing NCI-H460 MX20 cells was used to screen libraries of compounds. Out of a library of 7325 natural products a...
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| Asıl Yazarlar: | , , , , , , , |
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| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2007
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2760480/ https://ncbi.nlm.nih.gov/pubmed/18089721 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-07-0352 |
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