Identification of Compounds that Correlate with ABCG2 Transporter Function in the National Cancer Institute Anticancer Drug Screen

ABCG2 is an ATP-binding cassette transporter that counts multiple anticancer compounds among its substrates and is believed to regulate oral bioavailability as well as serve a protective role in the blood-brain barrier, the maternal-fetal barrier, and hematopoietic stem cells. We sought to determine...

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Main Authors: Deeken, John F., Robey, Robert W., Shukla, Suneet, Steadman, Kenneth, Chakraborty, Arup R., Poonkuzhali, Balasubramanian, Schuetz, Erin G., Holbeck, Susan, Ambudkar, Suresh V., Bates, Susan E.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Pharmacology and Experimental Therapeutics 2009
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2774997/
https://ncbi.nlm.nih.gov/pubmed/19633067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/mol.109.056192
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