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Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance

Lysine demethylase 5A (KDM5A/RBP2/JARID1A) is a histone lysine demethylase that is overexpressed in several human cancers including lung, gastric, breast and liver cancers. It plays key roles in important cancer processes including tumorigenesis, metastasis, and drug tolerance, making it a potential...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Oncotarget
Prif Awduron: Gale, Molly, Sayegh, Joyce, Cao, Jian, Norcia, Michael, Gareiss, Peter, Hoyer, Denton, Merkel, Jane S., Yan, Qin
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Impact Journals LLC 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5129982/
https://ncbi.nlm.nih.gov/pubmed/27224921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9539
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