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Screen-identified selective inhibitor of lysine demethylase 5A blocks cancer cell growth and drug resistance
Lysine demethylase 5A (KDM5A/RBP2/JARID1A) is a histone lysine demethylase that is overexpressed in several human cancers including lung, gastric, breast and liver cancers. It plays key roles in important cancer processes including tumorigenesis, metastasis, and drug tolerance, making it a potential...
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| Vydáno v: | Oncotarget |
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| Hlavní autoři: | , , , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Impact Journals LLC
2016
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5129982/ https://ncbi.nlm.nih.gov/pubmed/27224921 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9539 |
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