Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

S-Adenosyl-l-methionine (AdoMet or SAM)-dependent methyltransferases (MTase) catalyze the transfer of the activated methyl group from AdoMet to specific positions in DNA, RNA, proteins and small biomolecules. This natural methylation reaction can be expanded to a wide variety of alkylation reactions...

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Vydáno v:J Vis Exp
Hlavní autoři: Hanz, Gisela Maria, Jung, Britta, Giesbertz, Anna, Juhasz, Matyas, Weinhold, Elmar
Médium: Artigo
Jazyk:Inglês
Vydáno: MyJove Corporation 2014
Témata:
Biochemistry
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354249/
https://ncbi.nlm.nih.gov/pubmed/25490674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52014
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