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Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

Protein lysine methyltransferases (PKMTs) play crucial roles in normal physiology and disease processes. Profiling PKMT targets is an important but challenging task. With cancer-relevant G9a as a target, we have demonstrated the success in developing S-adenosyl-L-methionine (SAM) analogues, particul...

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Detalhes bibliográficos
Main Authors: Islam, Kabirul, Zheng, Weihong, Yu, Haiqiang, Deng, Haiteng, Luo, Minkui
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137739/
https://ncbi.nlm.nih.gov/pubmed/21495674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000567
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