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Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

Protein lysine methyltransferases (PKMTs) play crucial roles in normal physiology and disease processes. Profiling PKMT targets is an important but challenging task. With cancer-relevant G9a as a target, we have demonstrated the success in developing S-adenosyl-L-methionine (SAM) analogues, particul...

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Bibliografiska uppgifter
Huvudupphovsmän: Islam, Kabirul, Zheng, Weihong, Yu, Haiqiang, Deng, Haiteng, Luo, Minkui
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2011
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137739/
https://ncbi.nlm.nih.gov/pubmed/21495674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000567
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