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Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling

Protein lysine methyltransferases (PKMTs) play crucial roles in normal physiology and disease processes. Profiling PKMT targets is an important but challenging task. With cancer-relevant G9a as a target, we have demonstrated the success in developing S-adenosyl-L-methionine (SAM) analogues, particul...

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Hlavní autoři: Islam, Kabirul, Zheng, Weihong, Yu, Haiqiang, Deng, Haiteng, Luo, Minkui
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3137739/
https://ncbi.nlm.nih.gov/pubmed/21495674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000567
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