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Expanding Cofactor Repertoire of Protein Lysine Methyltransferase for Substrate Labeling
Protein lysine methyltransferases (PKMTs) play crucial roles in normal physiology and disease processes. Profiling PKMT targets is an important but challenging task. With cancer-relevant G9a as a target, we have demonstrated the success in developing S-adenosyl-L-methionine (SAM) analogues, particul...
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| Hauptverfasser: | , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3137739/ https://ncbi.nlm.nih.gov/pubmed/21495674 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb2000567 |
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