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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

S-Adenosyl-l-methionine (AdoMet or SAM)-dependent methyltransferases (MTase) catalyze the transfer of the activated methyl group from AdoMet to specific positions in DNA, RNA, proteins and small biomolecules. This natural methylation reaction can be expanded to a wide variety of alkylation reactions...

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Bibliografski detalji
Izdano u:J Vis Exp
Glavni autori: Hanz, Gisela Maria, Jung, Britta, Giesbertz, Anna, Juhasz, Matyas, Weinhold, Elmar
Format: Artigo
Jezik:Inglês
Izdano: MyJove Corporation 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354249/
https://ncbi.nlm.nih.gov/pubmed/25490674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52014
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