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Sequence-specific Labeling of Nucleic Acids and Proteins with Methyltransferases and Cofactor Analogues

S-Adenosyl-l-methionine (AdoMet or SAM)-dependent methyltransferases (MTase) catalyze the transfer of the activated methyl group from AdoMet to specific positions in DNA, RNA, proteins and small biomolecules. This natural methylation reaction can be expanded to a wide variety of alkylation reactions...

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Detalhes bibliográficos
Publicado no:J Vis Exp
Main Authors: Hanz, Gisela Maria, Jung, Britta, Giesbertz, Anna, Juhasz, Matyas, Weinhold, Elmar
Formato: Artigo
Idioma:Inglês
Publicado em: MyJove Corporation 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4354249/
https://ncbi.nlm.nih.gov/pubmed/25490674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3791/52014
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