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RB loss contributes to aggressive tumor phenotypes in MYC-driven triple negative breast cancer
Triple negative breast cancer (TNBC) is characterized by multiple genetic events occurring in concert to drive pathogenic features of the disease. Here we interrogated the coordinate impact of p53, RB, and MYC in a genetic model of TNBC, in parallel with the analysis of clinical specimens. Primary m...
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| Veröffentlicht in: | Cell Cycle |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Taylor & Francis
2015
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4353068/ https://ncbi.nlm.nih.gov/pubmed/25602521 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.967118 |
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