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RB restricts DNA damage initiated tumorigenesis through an LXCXE dependent mechanism of transcriptional control
The LXCXE peptide motif facilitates interaction between the RB tumor suppressor and a large number of cellular proteins that are expected to impinge on diverse biological processes. In vitro and in vivo analyses demonstrated that LXCXE-binding function is dispensable for RB promoter association and...
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| Publicado no: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4271833/ https://ncbi.nlm.nih.gov/pubmed/21855804 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.06.029 |
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