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RB loss contributes to aggressive tumor phenotypes in MYC-driven triple negative breast cancer

Triple negative breast cancer (TNBC) is characterized by multiple genetic events occurring in concert to drive pathogenic features of the disease. Here we interrogated the coordinate impact of p53, RB, and MYC in a genetic model of TNBC, in parallel with the analysis of clinical specimens. Primary m...

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Detalhes bibliográficos
Publicado no:Cell Cycle
Main Authors: Knudsen, Erik S, McClendon, A Kathleen, Franco, Jorge, Ertel, Adam, Fortina, Paolo, Witkiewicz, Agnieszka K
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4353068/
https://ncbi.nlm.nih.gov/pubmed/25602521
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/15384101.2014.967118
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