Učitavanje...
MLN4924 sensitizes monocytes and maturing dendritic cells for TNF-dependent and -independent necroptosis
BACKGROUND AND PURPOSE: MLN4924 prevents the formation of active cullin-RING ubiquitin ligase complexes and thus inhibits NF-κB signalling. Here, we evaluated the effects of this compound on monocytes and dendritic cells (DCs). EXPERIMENTAL APPROACH: Monocytes and DCs were challenged with TNF or LPS...
Spremljeno u:
| Izdano u: | Br J Pharmacol |
|---|---|
| Glavni autori: | , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
BlackWell Publishing Ltd
2015
|
| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4337697/ https://ncbi.nlm.nih.gov/pubmed/25363690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12998 |
| Oznake: |
Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!
|