SMAC Mimetic BV6 Induces Cell Death in Monocytes and Maturation of Monocyte-Derived Dendritic Cells

BACKGROUND: Compounds mimicking the inhibitory effect of SMAC / DIABLO on X-linked inhibitor of apoptosis (XIAP) have been developed with the aim to achieve sensitization for apoptosis of tumor cells resistant due to deregulated XIAP expression. It turned out that SMAC mimetics also have complex eff...

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Detalhes bibliográficos
Principais autores: Müller-Sienerth, Nicole, Dietz, Lena, Holtz, Philipp, Kapp, Markus, Grigoleit, Götz Ulrich, Schmuck, Carsten, Wajant, Harald, Siegmund, Daniela
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3127953/
https://ncbi.nlm.nih.gov/pubmed/21738708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0021556
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